I think only player character and level design and rewards …
I think only player character and level design and rewards would stay the same. @ACP_Nate did make the Save the miners game and every time You play enemies and levels are randomized and there are more games like that but I can't think of any of them atm.
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Yup. Save the Miners! randomizes map/maze layout, treasure chest locations and content, and monster variety and placement. I did have to preset the player's character, monster types, and map elements. I know a guy that is implementing AI in his card game - the art and stats are always new. Pretty cool ai integration. I need to learn how to do that:) https://www.acpnate.com/save-the-miners/