1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Gray hair is caused by loss of melanocytes (pigment cells) in the hair follicle. This happens as we age and, unfortunately, there is no treatment that can restore these cells and the pigment they produce, melanin.
https://twetch.app/t/23346bf8a1eedc16ce13e5213365cbf324c0c9b6c4ece52c4109861609a6f4ca
Replies
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Stress can cause hair to gray prematurely by affecting the stem cells that are responsible for regenerating hair pigment. The findings give insights for future research into how stress affects stem cells and tissue regeneration.
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
As we get older, the pigment cells in our hair follicles gradually die. When there are fewer pigment cells in a hair follicle, that strand of hair will no longer contain as much melanin and will become a more transparent color like gray, as it grows.
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
All cells experience changes with aging. They become larger and are less able to divide and multiply. Among other changes, there is an increase in pigments and fatty substances inside the cell (lipids)
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
A senescent cell is releasing the grey pigment and nearby cells are also effected become senescent and start to release that pigment. This is the reason your hair greys in patches.
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
As cells replicate, telomeres shorten at the end of chromosomes, and this process correlates to senescence or cellular aging. Integral to this process is telomerase, which is an enzyme that repairs telomeres and is present in various cells in the body.
https://twetch.app/t/271d1562cca5fa84616ac05ab2cdce3bdf7ff19f6957f28deaa4a8aa81142966
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Vitamin D-3, Vitamin B-12, and copper and their connection to graying hair. It finds nutritional deficiencies affect pigmentation, suggesting color can return with vitamin supplementation.
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Hormonal changes caused by a thyroid problem such as hyperthyroidism or hypothyroidism may also be responsible for premature white hair.
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
The age at which graying begins seems almost entirely due to genetics. Sometimes people are born with gray hair because they inherit the trait.
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Estrogen increased pheomelanin content in female hair, whereas the hormone greatly decreased both eumelanin and pheomelanin content in male hair. High doses of progesterone, in contrast, increased total melanin content in both female and male hair.
https://twetch.app/t/2dda2740b9dd1cf547c4dc433a4d3ce44b5a11831021a91d0898decb16ce9891
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
The graying of hair with increasing age is an early sign of increased oxidative stress in skin tissues around hair follicles.
https://twetch.app/t/ec87602454bb4067425806db8cd0fd582a6646d6a212e379c065eb6b3986977b
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Noradrenaline, also known as norepinephrine, was key to stress-induced hair graying. By injecting noradrenaline under the skin of unstressed mice, the researchers were able to cause melanocyte stem cell loss and hair graying.
https://twetch.app/t/5d5bacc4614f328316d174ff1a3ae8725c904d6adcc6bd0017b9382f19c1a11e
1EFyYrZ3NBGLdzwcbeXsDE2TkZUFeqEvi1 (2755) ·
Sympathetic nerves extend into each hair follicle and release noradrenaline in response to stress. Normally, the melanocyte stem cells in the follicle are dormant until a new hair is grown. Noradrenaline causes the stem cells to activate.
https://twetch.app/t/8946ac06296e65dc5235c14527dbbe5f8c1fdc569c62513fdd0a370f97bfb84e